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March Madness: Final Four Picks and Odds

Kyle Terada-USA TODAY Sports

There is virtually always at least one massive bracket buster that reaches the Final Four. Last year, we saw Loyola-Chicago and Sister Jean make their magical run to be one of the last four teams with a shot at winning the national championship. In each of the last six seasons, at least one No. 7 seed or higher has made it to the third week of the NCAA Tournament.

The key is determining which region is most likely to produce an upset winner and going forward accordingly. No. 1 seeds are No. 1 seeds for a reason and about half of the teams that have been put on the No. 1 line have made it to the Final Four since the field expanded to 64 teams in 1985. With that in mind, here are my picks (in bold) to win each region. You can bet all the NCAA Tournament Regional winners at BetDSI.

East Region Winner

Duke -182

Michigan State +340

Virginia Tech +700

LSU +1200

Louisville +1400

Mississippi State +1900

Maryland +2400

Belmont +2400

VCU +4900

Central Florida +4900

Minnesota +5900

Saint Louis +7900

Yale +7900

Liberty +9400

Bradley +9400

North Dakota State +19400

This is a strategic pick for your bracket and a value pick for the odds. Duke is the only odds-on favorite to win their region, and the odds on the Blue Devils to win the NCAA Tournament are ridiculously low. There isn’t much value in taking Duke to win the East Region, and Michigan State has been nearly as good as Duke according to Ken Pomeroy’s advanced numbers.

The return of Nick Ward has made the Spartans a real contender, and this team is one of the best rebounding teams in the country. Their offense has been very reliable as they have assists on more than 68 percent of their made field goals (the best rate in the country), and Cassius Winston could have a huge game.

South Region Winner

Virginia +100

Tennessee +275

Purdue +500

Villanova +800

Kansas State +1000

Cincinnati +1400

Wisconsin +2200

Mississippi +3000

Oregon +3000

St. Mary’s +4000

Oklahoma +5000

Iowa +5000

UC Irvine +7500

Old Dominion +8000

Colgate +20100

Gardner-Webb +20100

I think this is the weakest region of them all, and I love Virginia’s chances to get through. The Cavaliers shouldn’t be tested in the first three rounds and I think there’s a good chance they don’t play No. 4 Kansas State or No. 5 Wisconsin in the Sweet 16.

A lot of people will dismiss Virginia outright after becoming the first No. 1 seed to lose to a No. 16 seed last year, but the Cavaliers are a veteran team with three dynamite shooters and they have one of the best defenses in the country. They should win their region.

West Region Winner

Gonzaga -118

Michigan +300

Texas Tech +450

Florida State +550

Buffalo +1100

Marquette +1500

Nevada +1700

Syracuse +2500

Florida +3000

Murray State +4000

Baylor +7400

Arizona State +10000

Vermont +10000

Northern Kentucky +10000

Montana +10000

Fairleigh Dickinson +15000

I’m tempted to go with Michigan, but the Bulldogs are just too strong. This Gonzaga team is loaded with talent, and they were the only team to beat Duke when the Blue Devils were fully healthy. They can get points from six different players, and their ability to lock opponents down on defense can’t be overstated. Gonzaga is the most talented team in the region, and they obviously have the best coach too.

Midwest Region Winner

North Carolina +162

Kentucky +240

Houston +485

Auburn +750

Iowa State +750

Wofford +1400

Utah State +1900

Seton Hall +4300

Washington +5000

Ohio State +5000

New Mexico State +7000

Northeastern +8000

Georgia State +8000

Abilene Christian +20000

Iona +20000

This is the region most likely to go awry. A number of teams could win the Midwest. A dangerous blue blood is lurking in Kansas, and two of the best mid-majors in the country (Wofford and Utah State) could play spoiler too.

UNC shouldn’t have received a No. 1 seed, and the Tar Heels are a team susceptible to big, physical opponents. That’s why I like Auburn’s chances. The Tigers can be physical, and they are the 13th best team in the country according to Pomeroy. That places them as the third-best team in the region, and they ended the season on a high note by beating Tennessee for the SEC Championship.

Written by Jonathan Willis

Jonathan Willis has written on virtually every sport imaginable over the last decade. His specialties are college football, eSports, politics, the NFL and the NHL. He is always looking for soft markets to pounce on, and he will have you in the black by the end of the year.

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