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Home » Blog » San Diego Padres vs. San Francisco Giants Matchup 09/26/18
MLB

San Diego Padres vs. San Francisco Giants Matchup 09/26/18

GMS Previews
Last updated: November 9, 2025 9:18 am
GMS Previews
5 Min Read
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Jake Roth-USA TODAY Sports

The San Diego Padres will be facing off against their divisional nemesis San Francisco Giants at AT&T Park. Fox Sports San Diego will be showing the matchup and the first pitch will be at 10:15 p.m. ET.

Contents
  • San Diego Padres at San Francisco Giants Odds
  • San Diego Padres at San Francisco Giants MLB Pick
  • Notes

San Diego Padres at San Francisco Giants Odds

Oddsmakers have listed San Francisco (-145) as the favorite over San Diego (+135). Bettors can wager on the game’s total with odds sitting at -105 for over 7 runs and -115 for under 7. Gamblers can also wager on the game’s spread with the current runline odds sitting at -160 for the Padres +1.5 runs and +140 for the Giants -1.5.

The Giants are 85-72 against the spread (ATS)despite being only 73-85 straight up (SU). They’ve lost 5.7 units for bettors taking the moneyline while earning 7.4 units (ATS). The Padres have gone 63-95 SU this year and are 75-82 ATS. Overall, the team’s lost 12.6 units for gamblers taking the moneyline and 28.9 units ATS.

San Francisco games have a 66-85-6 over/under record in 2018. The Padres have an over/under record of 76-75-6.

Right-hander Luis Perdomo will get the nod for the visiting Padres. Perdomo (1-6, 7.56 ERA) has recorded 35 punchouts in 41.2 innings so far. He has yet to face San Francisco this year, but he made five starts against the Giants in 2017, putting together a 1-0 record against them with a 3.56 ERA and 19 strikeouts.

The Giants are sending righty Casey Kelly (0-2, 2.89 ERA) to the mound. Kelly has 13 strikeouts and five walks to his name, as well as a WHIP of 1.45. Kelly did not pitch in the majors last season.

San Diego’s pitching staff allowed 4.8 runs per game and its starting pitchers own a 5.16 ERA, 1.46 WHIP and 7.39 K/9. The bullpen has logged an ERA of 3.59, along with a WHIP of 1.46 and a K-per-9 of 10.23.

Padres hitters have slashed .235/.299/.380 on their way to 3.8 runs scored per game in 2018, including 3.6 runs per game against divisional foes and 3.2 per game over the team’s last five contests (2-3 SU).

San Diego’s hitters have been paced by first baseman Eric Hosmer and shortstop Freddy Galvis, who’ve collectively blasted 30 home runs. Hosmer is slashing .250/.316/.393 with 17 home runs, 67 RBIs and 71 runs scored, while Galvis (.246/.299/.378) is up to 13 homers, 66 RBIs and 60 runs scored.

In the other dugout, San Francisco’s pitching staff has yielded 4.2 runs per game overall this season. The club’s starters have a 3.97 ERA, 1.31 WHIP and 7.1 strikeouts per nine innings. The bullpen has a 3.68 ERA, 1.27 WHIP and 8.9 K/9. In 72 divisional games, Giants starters have an ERA of 3.77 and the bullpen’s ERA is 3.10.

The San Francisco hitters are putting up 3.8 runs per outing, including 3.7 per game against divisional foes and 2.8 per game over their last five. The team has slashed .216/.260/.303 over its last five contests and is 1-4 SU during that span.

The Giants’ offense has been led by shortstop Brandon Crawford and right fielder Andrew McCutchen. Crawford is slashing .255/.321/.396 with 14 home runs, 54 RBIs and 61 runs scored, and McCutchen’s line sits at .255/.357/.415 with 15 homers, 55 RBIs and 65 runs scored.

San Diego Padres at San Francisco Giants MLB Pick

Predictions: SU Winner – Giants, ATS Winner – Padres, O/U – UNDER

Click Here to Start Betting Today!

Notes

Betting Notes

The over has cashed in four of San Diego’s last seven games.

San Diego has posted 21.0 Runs + Hits + Errors per game over its last 10 contests and 21.2 over its last five.

The Padres have hit 11 home runs in their last 10 games. The Giants have hit six over their last 10.

*****

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TAGGED:MLBSan Diego PadresSan Francisco Giants
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