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Home » Blog » Chicago Cubs vs. Chicago White Sox Free Pick 09/22/18
MLB

Chicago Cubs vs. Chicago White Sox Free Pick 09/22/18

GMS Previews
Last updated: November 9, 2025 10:00 am
GMS Previews
6 Min Read
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Cubs vs Reds
David Kohl-USA TODAY Sports

The Chicago Cubs are set to face the Chicago White Sox at Guaranteed Rate Field. NBC Sports Chicago will be televising this interleague matchup. The first pitch is scheduled for 7:10 p.m. ET.

Contents
  • Chicago Cubs vs. Chicago White Sox Odds
  • Chicago Cubs vs. Chicago White Sox Free MLB Tip
  • Notes

Chicago Cubs vs. Chicago White Sox Odds

Vegas is listing The Cubs (-185) as the favorite over the White Sox (+175). The total is sitting at 9 runs and bettors can take the over for -120 and the under for an even +100. Bettors can also wager on the game’s spread with the current runline odds sitting at -130 for the Cubs -1.5 runs and +110 for the White Sox +1.5.

The White Sox are 78-74 against the spread (ATS), but just 61-92 straight up (SU). They’ve lost 14.3 units for bettors taking the moneyline and 1.9 units (ATS). They’ve covered the spread four times in their last seven games and the total has gone under in four of those seven. The Cubs are 89-64 SU and have gone 75-77 ATS. Overall, the team’s accumulated 3.5 units for moneyline bettors, but have lost 2.0 units ATS. They’ve covered the spread only twice over their last seven games and the total has gone under in five of those seven.

White Sox games have an over/under record of 70-74-8 in 2018. The Cubs have been a good under bet with a total record of 67-82-3.

Jon Lester will get the start for the visiting Cubs. The southpaw Lester is 16-6 with a 3.43 ERA and 142 strikeouts. He’s 1-0 with five strikeouts and a 1.59 ERA against the White Sox this year.

The White Sox will put the ball in the right hand of Lucas Giolito (10-11, 5.77 ERA), who has 118 punchouts and 83 walks as well as a 1.43 WHIP. Giolito is 1-0 with three strikeouts and a 4.76 ERA in one start against the Cubs this year.

the Cubs’ pitching staff allowed 4.0 runs per game and their starting pitchers own a 3.92 ERA, 1.34 WHIP and 7.88 K/9. The bullpen has an ERA of 3.37, along with a WHIP of 1.34 and a K-per-9 of 8.59.

The Cubs offense has slashed .259/.336/.412 on its way to 4.7 runs scored per game this season, including 3.1 runs per game over the team’s last 10 games and 3.8 per game over the team’s last five outings (2-3 SU).

Chicago’s offensive production has been powered by second baseman Javier Baez and first baseman Anthony Rizzo, who collectively have swatted 57 home runs. Baez is hitting .292/.327/.565 with 33 home runs, 107 RBIs, 96 runs and 21 stolen bases, while Rizzo (.278/.374/.465) has produced 24 homers, 95 RBIs and 68 runs scored.

For the home team, the White Sox’ pitching staff has allowed 5.2 runs per game overall in 2018. Their starting pitching staff has an ERA of 4.88, a WHIP of 1.38 and a strikeouts-per-nine of 6.8. The bullpen has a 4.51 ERA, 1.46 WHIP and 9.7 K/9.

The Chicago offense has produced 4.1 runs per contest, including 4.3 per game over its last 10 games and 4.6 per game over its last five. The team has slashed .276/.335/.458 over its last five matchups and is 2-3 SU during that stretch.

Third baseman Yolmer Sanchez and shortstop Tim Anderson have paced the White Sox hitters this year. Sanchez is slashing .248/.315/.381 with eight home runs, 52 RBIs, 57 runs and 14 stolen bases, and Anderson’s line is .241/.282/.405 with 19 homers, 62 RBIs, 74 runs and 26 stolen bases.

The Cubs have gained 0.7 units and are 58-60 ATS when facing a righty starter this season. The over has hit in 51 of those games, compared to 64 that’ve gone under in such games. On the other hand, the White Sox have lost 5.4 units and are 20-18 ATS when facing a left-handed starting pitcher. The over has hit in 16 of those games, compared to 21 which went under the total.

Chicago Cubs vs. Chicago White Sox Free MLB Tip

Predictions: SU Winner – Cubs, ATS Winner – Cubs, O/U – OVER

Click Here to Start Betting Today!

Notes

Betting Trends

Chicago has logged 11 extra-base hits over its last five contests. Chicago has 17 XBH over its last five.

The Cubs have recorded 16.3 Runs + Hits + Errors per game over their last 10 outings and 18.2 over their last five.

The Cubs have hit seven home runs in their last 10 games, including five over their last five.

*****

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